Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.53 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8638520 | 1.00 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8638566 | 0.90 | SMN1; SMN2 (0.65) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8638570 | 0.90 | SMN1; SMN2 (0.65) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8637357 | 0.85 | SMN1; SMN2 (0.64) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8637365 | 0.85 | SMN1; SMN2 (0.64) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8637112 | 0.85 | MEN1 (0.69) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8637121 | 0.85 | MEN1 (0.69) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8637338 | 0.83 | SMN1; SMN2 (0.66) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8637332 | 0.83 | SMN1; SMN2 (0.66) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8635549 | 0.80 | KMT2A (0.70) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |