Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28831505 | 0.90 | GAA (0.39) | MAPTGAA | |
| SCHEMBL4250724 | 0.83 | GAA (0.36) | MAPTGAA | |
| Hydrochloric Acid SCHEMBL8805169 | 0.82 | GAA (0.36) | MAPTGAA | |
| SCHEMBL9527218 | 0.77 | GAA (0.38) | MAPTGAA | |
| SCHEMBL11389449 | 0.77 | GAA (0.38) | MAPTGAA | |
| SCHEMBL9789197 | 0.77 | GAA (0.38) | MAPTGAA | |
| SCHEMBL11882072 | 0.73 | GAA (0.34) | MAPTGAA | |
| SCHEMBL28905184 | 0.73 | GAA (0.32) | MAPTGAA | |
| SCHEMBL29133228 | 0.72 | KDM4E (0.38) | MAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL11802682 | 0.71 | EPHX2 (0.35) | MAPTGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730456-A4 | ANTIARRHYTHMIC BENZODIAZEPINES | MERCK & CO INC (US) | 1998-02-04 | — | — | EP | disclosed |
| EP-0730456-A1 | ANTIARRHYTHMIC BENZODIAZEPINES | MERCK & CO. INC. (US) | 1996-09-11 | — | — | EP | disclosed |
| WO-1995014472-A1 | ANTIARRHYTHMIC BENZODIAZEPINES | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | disclosed |