Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641352 | 0.96 | HRH3 (0.40) | RARBHSD11B1HRH3HSD17B10ALDH1A1 | |
| SCHEMBL8638854 | 0.94 | HSD17B10 (0.41) | RARBHRH3HSD17B10ALDH1A1HPGD | |
| SCHEMBL8639240 | 0.94 | HSD17B10 (0.41) | RARBHRH3HSD17B10ALDH1A1HPGD | |
| SCHEMBL8639433 | 0.92 | HSD17B10 (0.38) | RARBNISCHHRH3HSD17B10ALDH1A1 | |
| SCHEMBL8636619 | 0.92 | HSD17B10 (0.38) | RARBNISCHHRH3HSD17B10ALDH1A1 | |
| SCHEMBL8637624 | 0.92 | HSD17B10 (0.38) | RARBNISCHHRH3HSD17B10ALDH1A1 | |
| SCHEMBL8640365 | 0.89 | HSD17B10 (0.41) | RARBHRH3HSD17B10ALDH1A1HPGD | |
| SCHEMBL8639173 | 0.89 | HSD17B10 (0.41) | RARBHRH3HSD17B10ALDH1A1HPGD | |
| SCHEMBL8637620 | 0.89 | HSD17B10 (0.41) | RARBHRH3HSD17B10ALDH1A1HPGD | |
| SCHEMBL8640257 | 0.89 | HSD17B10 (0.41) | RARBHRH3HSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5342546-A | Liquid crystal compositions | L.C.C. CONSULTANTS CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |