⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14891685 | 0.97 | — | — | |
| SCHEMBL14891669 | 0.92 | — | — | |
| SCHEMBL5049145 | 0.80 | — | — | |
| SCHEMBL3586141 | 0.79 | — | — | |
| SCHEMBL639516 | 0.78 | EPHX1 (0.64) | — | |
| SCHEMBL3965054 | 0.78 | EPHX1 (0.64) | — | |
| SCHEMBL8376278 | 0.78 | EPHX1 (0.64) | — | |
| SCHEMBL8694784 | 0.78 | — | — | |
| SCHEMBL8374773 | 0.78 | EPHX1 (0.64) | — | |
| SCHEMBL8375291 | 0.78 | EPHX1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187450-B2 | Substituted pyridine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-11-17 | — | — | US | disclosed |
| EP-2592076-B1 | SUBSTITUTED PYRIDINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2015-05-13 | — | — | EP | disclosed |
| US-20140213549-A9 | Substituted Pyridine Compound | UBE INDUSTRIES, LTD. (JP) | 2014-07-31 | — | — | US | disclosed |
| US-20140005143-A2 | Substituted PyridineCompound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-01-02 | — | — | US | disclosed |
| EP-2592076-A1 | SUBSTITUTED PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-05-15 | — | — | EP | disclosed |
| US-20130109653-A1 | Substituted Pyridine Compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-02 | — | — | US | disclosed |
| EP-0680948-B1 | Process for preparing N-acylglycin derivatives | HOECHST AG (DE) | 1998-04-08 | — | — | EP | disclosed |
| US-5650537-A | REACTION OF AMIDE WITH ALDEHYDE THEN CARBONYLATION IN THE PRESENCE OF COBALT CARBONYL | HOECHST AG (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0680948-A1 | Process for preparing N-acylglycin derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-08 | — | — | EP | disclosed |