Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6762091 | 0.84 | MEN1 (0.55) | MEN1KMT2ACYP4F2CYP4A11TSHR | |
| SCHEMBL11783157 | 0.84 | CYP4F2 (0.46) | MEN1KMT2ACYP4F2CYP4A11GPR84 | |
| SCHEMBL22190459 | 0.84 | CYP4F2 (0.69) | MEN1KMT2ACYP4F2CYP4A11GPR84 | |
| SCHEMBL11063113 | 0.82 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL183166 | 0.82 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL7516322 | 0.82 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL7516454 | 0.82 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL8216269 | 0.82 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL21046041 | 0.82 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT | |
| SCHEMBL11001712 | 0.82 | MEN1 (0.59) | MEN1KMT2ACYP4F2CYP4A11HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594577-B1 | NOVEL POTENT INDUCERS OF TERMINAL DIFFERENTIATION AND METHOD OF USE THEREOF | SLOAN KETTERING INST CANCER (US) | 1998-12-30 | — | — | EP | disclosed |
| US-5840960-A | ANTITUMOR | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-11-24 | — | — | US | disclosed |
| US-5608108-A | ANTITUMOR AGENTS; LUNG, BLADDER, KIDNEY, BREAST, COLORECTAL | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1997-03-04 | — | — | US | disclosed |
| US-5175191-A | Antitumor agents or anticancer agents | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-12-29 | — | — | US | disclosed |
| WO-1991000257-A1 | NOVEL POTENT INDUCERS OF TERMINAL DIFFERENTIATION AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1991-01-10 | — | — | WO | disclosed |