Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MVD | P53602 | 1/20 | 0.36 |
| ▸ | BHMT | Q93088 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641901 | 0.83 | GMNN (0.43) | TSHRMAPTGMNNTP53POLB | |
| SCHEMBL3913020 | 0.83 | TSHR (0.56) | TSHREPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL322326 | 0.82 | MEN1 (0.50) | TSHRMAPTEPHX1GMNNTP53 | |
| SCHEMBL16923030 | 0.81 | TSHR (0.41) | TSHRMAPTEPHX1TP53POLB | |
| SCHEMBL11193449 | 0.79 | TSHR (0.71) | TSHRMAPTGMNNTP53POLB | |
| SCHEMBL9402108 | 0.78 | TSHR (0.45) | TSHRMAPTEPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11195997 | 0.75 | CYP2D6 (0.46) | TSHRMAPTGMNNTP53POLB | |
| SCHEMBL8641912 | 0.74 | MAPT (0.46) | TSHRMAPTEPHX1GMNNTP53 | |
| SCHEMBL13627873 | 0.74 | — | — | |
| SCHEMBL18653784 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756822-A | ANTIULCER | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| US-5672597-A | ANTIULCER AGENT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0673925-A1 | ACETAMIDE DERIVATIVE | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1995-09-27 | — | — | EP | disclosed |