⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708177 | 0.85 | — | — | |
| SCHEMBL127131 | 0.78 | — | — | |
| SCHEMBL13019561 | 0.78 | — | — | |
| SCHEMBL536615 | 0.74 | — | — | |
| SCHEMBL1671480 | 0.74 | — | — | |
| SCHEMBL11641727 | 0.74 | — | — | |
| SCHEMBL910874 | 0.72 | — | — | |
| SCHEMBL8551633 | 0.72 | SMN1; SMN2 (0.35) | — | |
| Water SCHEMBL190313 | 0.72 | MAPT (0.46) | — | |
| Hydrochloric Acid SCHEMBL11187707 | 0.72 | NPC1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101003512-B | Method for preparing methylamino uracil | SHANGHAI CHEMICAL REAGENT RES INST | 2011-03-16 | — | — | CN | disclosed |
| CN-101003512-B | Method for preparing methylamino uracil | SHANGHAI CHEMICAL REAGENT RES INST | 2011-03-16 | — | — | CN | disclosed |
| CN-101003512-A | Method for preparing methylamino uracil | SHANGHAI INST OF CHEMICAL AGEN (CN) | 2007-07-25 | — | — | CN | disclosed |
| CN-101003512-A | Method for preparing methylamino uracil | SHANGHAI INST OF CHEMICAL AGEN (CN) | 2007-07-25 | — | — | CN | disclosed |
| EP-0664014-B1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | AKZO NOBEL NV (NL) | 1998-08-19 | — | — | EP | disclosed |
| EP-0824096-A2 | Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters | Akzo Nobel N.V. (NL) | 1998-02-18 | — | — | EP | disclosed |
| EP-0664014-A1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | Akzo Nobel N.V. (NL) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008269-A1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | AKZO NOBEL N.V. (NL) | 1994-04-14 | — | — | WO | disclosed |
| US-4659827-A | Process for producing 2,4,5,6-tetrachloropyrimidine by way of 5,6-dichloro-2,4-dihydroxypyrimidine which was produced from the corresponding 5,6-dichloro-2,4-di(trihalomethyl)-pyrimidine and a process for producing 2,4-dihydroxypyrimidine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| EP-0182190-A2 | Process for the preparation of 2,4-dihydroxypyrimidines | BAYER AG (DE) | 1986-05-28 | — | — | EP | disclosed |