Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.52 |
| ▸ | GUSB | P08236 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639464 | 1.00 | BCHE (0.52) | BCHEGUSBHTR1AGNAI3GNAO1 | |
| SCHEMBL27554647 | 0.91 | BCHE (0.60) | BCHEGUSBHTR1AGNAI3GNAO1 | |
| Methane SCHEMBL6602166 | 0.89 | BCHE (0.59) | BCHEGUSBHTR1AGNAI3GNAO1 | |
| Methane SCHEMBL7056640 | 0.89 | BCHE (0.59) | BCHEGUSBHTR1AGNAI3GNAO1 | |
| SCHEMBL14638881 | 0.89 | BCHE (0.58) | BCHEGUSBHTR1AGNAI3GNAO1 | |
| SCHEMBL8298490 | 0.89 | BCHE (0.58) | BCHEGUSBHTR1AGNAI3GNAO1 | |
| SCHEMBL30964727 | 0.84 | BCHE (0.43) | BCHEHTR1A | |
| SCHEMBL24114600 | 0.84 | BCHE (0.51) | BCHEGUSBHTR1A | |
| SCHEMBL12157375 | 0.84 | BCHE (0.51) | BCHEGUSBHTR1A | |
| SCHEMBL6627539 | 0.84 | BCHE (0.51) | BCHEGUSBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650474-B1 | NOVEL PIPERIDYL AMIDES, SULFONAMIDES AND SULFOXAMIDES AS INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | MERRELL PHARMA INC (US) | 1998-08-12 | — | — | EP | claimed |