Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | HTR2C | P28335 | 1/20 | 0.73 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639752 | 1.00 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL23424127 | 0.90 | CYP1A1 (0.62) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL13168898 | 0.89 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL11226250 | 0.88 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL11226247 | 0.88 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL13168900 | 0.88 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL14038906 | 0.88 | GAA (0.73) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL14038898 | 0.86 | CYP1A1 (0.62) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL13168901 | 0.86 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL13168904 | 0.86 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| US-4337270-A | ANTIALLERGENS; ANTIANAPHYLACTIC AGENTS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1982-06-29 | — | — | US | disclosed |