Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639772 | 1.00 | CA14 (0.52) | CA14TDP1MEN1KMT2AGAA | |
| SCHEMBL8640276 | 0.95 | CA14 (0.52) | CA14TDP1MEN1KMT2AGAA | |
| SCHEMBL8640270 | 0.95 | CA14 (0.52) | CA14TDP1MEN1KMT2AGAA | |
| SCHEMBL8641808 | 0.92 | CA14 (0.56) | CA14TDP1MEN1KMT2AGAA | |
| SCHEMBL8641799 | 0.92 | CA14 (0.56) | CA14TDP1MEN1KMT2AGAA | |
| SCHEMBL8638135 | 0.91 | CA14 (0.50) | CA14TDP1MEN1KMT2AGAA | |
| SCHEMBL8638124 | 0.91 | CA14 (0.50) | CA14TDP1MEN1KMT2AGAA | |
| SCHEMBL18950461 | 0.90 | CA14 (0.63) | CA14TDP1MEN1KMT2AGAA | |
| SCHEMBL8640041 | 0.88 | CA14 (0.46) | CA14CA12CA1CA7CA2 | |
| SCHEMBL8640034 | 0.88 | CA14 (0.46) | CA14CA12CA1CA7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686143-B1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA GEIGY AG (CH) | 1998-08-12 | — | — | EP | disclosed |
| US-5627215-A | Unsaturate amino compounds for use as anticancer and antiprotozoic agent | CIBA-GEIGY CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0686143-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | Novartis AG (CH) | 1995-12-13 | — | — | EP | disclosed |
| WO-1995018091-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA-GEIGY AG (CH) | 1995-07-06 | — | — | WO | disclosed |