Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640304 | 1.00 | KMT2A (0.56) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8649491 | 0.82 | KMT2A (0.60) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8644761 | 0.82 | KMT2A (0.60) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8647579 | 0.79 | KMT2A (0.60) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8647576 | 0.79 | KMT2A (0.60) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8647531 | 0.78 | KMT2A (0.58) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8646173 | 0.78 | KMT2A (0.58) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8646167 | 0.78 | KMT2A (0.58) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8618446 | 0.76 | CHRM1 (0.58) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8618442 | 0.76 | CHRM1 (0.58) | KMT2ACHRM1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674636-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LTD (GB) | 1998-05-20 | — | — | EP | disclosed |