Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639402 | 0.96 | SCN9A (0.57) | SCN9AHRH3HRH1MAOBMAOA | |
| SCHEMBL8640727 | 0.88 | SCN9A (0.79) | SCN9AHRH3HRH1MAOBMAOA | |
| SCHEMBL9133333 | 0.88 | HRH3 (0.57) | SCN9AHRH3HRH1MAOBMAOA | |
| SCHEMBL8637430 | 0.88 | SCN9A (0.79) | SCN9AHRH3HRH1MAOBMAOA | |
| SCHEMBL966440 | 0.87 | SCN9A (0.75) | SCN9AHRH3MAOBMAOA | |
| SCHEMBL2186343 | 0.87 | SCN9A (0.75) | SCN9AHRH3MAOBMAOA | |
| SCHEMBL2187391 | 0.87 | SCN9A (0.75) | SCN9AHRH3MAOBMAOA | |
| SCHEMBL8639759 | 0.87 | SCN9A (0.61) | SCN9AHRH3HRH1MAOBMAOA | |
| SCHEMBL9132041 | 0.86 | SCN9A (0.60) | SCN9AHRH3HRH1MAOBMAOA | |
| SCHEMBL1067813 | 0.85 | HRH3 (0.61) | SCN9AHRH3HRH1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643688-B1 | SUBSTITUTED (ARYLALKOXYBENZYL)AMINOPROPANAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS | PHARMACIA & UPJOHN SPA (IT) | 1998-07-29 | — | — | EP | claimed |
| US-5446066-A | Antiepileptic, antidepressants, antispastic agent | FARMITALIA CARLO ERBA S.R.L. (IT) | 1995-08-29 | — | — | US | claimed |
| EP-0643688-B1 | SUBSTITUTED (ARYLALKOXYBENZYL)AMINOPROPANAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-EPILEPTIC, NEUROPROTECTIVE AND ANTIDEPRESSANT AGENTS | PHARMACIA & UPJOHN SPA (IT) | 1998-07-29 | — | — | EP | disclosed |
| US-5446066-A | Antiepileptic, antidepressants, antispastic agent | FARMITALIA CARLO ERBA S.R.L. (IT) | 1995-08-29 | — | — | US | disclosed |