Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | SHBG | P04278 | 2/20 | 0.57 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641143 | 1.00 | CYP19A1 (0.80) | CYP19A1CYP3A4SHBGSERPINA6AR | |
| SCHEMBL9066081 | 0.89 | SERPINA6 (0.72) | CYP19A1CYP3A4SHBGSERPINA6AR | |
| SCHEMBL10273391 | 0.89 | SERPINA6 (0.72) | CYP19A1CYP3A4SHBGSERPINA6AR | |
| SCHEMBL9066088 | 0.89 | SERPINA6 (0.72) | CYP19A1CYP3A4SHBGSERPINA6AR | |
| SCHEMBL8645662 | 0.88 | CYP19A1 (0.63) | CYP19A1CYP3A4SHBGSERPINA6AR | |
| SCHEMBL9549867 | 0.88 | AR (0.70) | CYP19A1CYP3A4SHBGSERPINA6AR | |
| SCHEMBL5708096 | 0.88 | AR (0.70) | CYP19A1CYP3A4SHBGSERPINA6AR | |
| SCHEMBL8645665 | 0.88 | CYP19A1 (0.63) | CYP19A1CYP3A4SHBGSERPINA6AR | |
| SCHEMBL5708095 | 0.88 | AR (0.70) | CYP19A1CYP3A4SHBGSERPINA6AR | |
| SCHEMBL9467827 | 0.84 | SERPINA6 (0.78) | CYP19A1CYP3A4SHBGSERPINA6AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804576-A | CANCER PREVENTIVE AGENTS, ANTI-OBESITY AGENTS, TREATMENT OF DIABETES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-09-08 | — | — | US | disclosed |
| US-5714481-A | ADMINISTERING TO MAMMALIAN HOST A GLUCOSE-6-PHSOPHATE DEHYDROGENASE INHIBITOR, ANTICARCINOGENIC, ANTIOBASITY, ANTI-HYPERGLYCEMIC, ANTIAGING, ANTICHOLESTEROL AND ANTI-AUTOIMMUNE AGENT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0133995-B1 | STEROIDS AND THERAPEUTIC COMPOSITIONS CONTAINING SAME | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-04-15 | — | — | EP | disclosed |
| US-5001119-A | 16-substituted androstanes and 16-substituted androstenes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1991-03-19 | — | — | US | disclosed |
| US-4898694-A | 17-Hydroxy-steroids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1990-02-06 | — | — | US | disclosed |
| EP-0133995-A2 | Steroids and therapeutic compositions containing same | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1985-03-13 | — | — | EP | disclosed |