Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 1.00 |
| ▸ | KDM4A | O75164 | 2/20 | 1.00 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 1.00 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 1.00 |
| ▸ | TET3 | O43151 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032 | 1.00 | TET2 (1.00) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL465914 | 1.00 | TET2 (1.00) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL7509 | 1.00 | TET2 (1.00) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL31620639 | 1.00 | TET2 (1.00) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL29844290 | 1.00 | TET2 (1.00) | TET2KDM4AKDM4CKDM2ATET3 | |
| Water SCHEMBL23358414 | 0.97 | TET2 (0.94) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL839512 | 0.97 | TET2 (0.94) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL20598827 | 0.97 | TET2 (0.94) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL19554357 | 0.97 | TET2 (0.94) | TET2KDM4AKDM4CKDM2ATET3 | |
| Lithium SCHEMBL31357194 | 0.97 | TET2 (0.94) | TET2KDM4AKDM4CKDM2ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12429423-B2 | L-2-hydroxyglutarate biosensor based on specific transcriptional regulator and application thereof | SHANDONG UNIVERSITY (CN) | 2025-09-30 | — | — | US | claimed |
| EP-3453046-B1 | GLUTARATE COMPOUNDS FOR TREATING ISCHEMIA-REPERFUSION INJURIES | UNIV CALIFORNIA (US) | 2025-07-09 | — | — | EP | claimed |
| US-20250000903-A1 | EXPANSION PROCESSES AND AGENTS FOR TUMOR INFILTRATING LYMPHOCYTES | IOVANCE BIOTHERAPEUTICS, INC. | 2025-01-02 | — | — | US | claimed |
| EP-4404969-A1 | EXPANSION PROCESSES AND AGENTS FOR TUMOR INFILTRATING LYMPHOCYTES | Iovance Biotherapeutics, Inc. (US) | 2024-07-31 | — | — | EP | claimed |
| CN-118243924-A | Serum metabolic marker for diagnosing or monitoring bladder cancer and application thereof | 宁夏医科大学总医院 | 2024-06-25 | — | — | CN | claimed |
| CN-118105416-A | Application of Hericium coralloides in preparing medicine for treating depression induced by lipid metabolism abnormality | 吉林农业大学 | 2024-05-31 | — | — | CN | claimed |
| US-11788112-B2 | L-2-hydroxyglutarate and stress induced metabolism | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2023-10-17 | — | — | US | claimed |
| CN-116660543-A | Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof | 中国人民解放军陆军军医大学第一附属医院 | 2023-08-29 | — | — | CN | claimed |
| WO-2023049862-A1 | EXPANSION PROCESSES AND AGENTS FOR TUMOR INFILTRATING LYMPHOCYTES | IOVANCE BIOTHERAPEUTICS, INC. (US) | 2023-03-30 | — | — | WO | claimed |
| CN-115856173-A | Detection method of central carbon and amino acid and application thereof | 北京诺禾致源科技股份有限公司 | 2023-03-28 | — | — | CN | claimed |
| WO-2017192413-A1 | GLUTARATE COMPOUNDS FOR TREATING ISCHEMIA-REPERFUSION INJURIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017189528-A1 | CORROSION INHIBITOR COMPOSITIONS AND METHODS OF USING SAME | Ecolab USA, Inc. (US) | 2017-11-02 | — | — | WO | claimed |
| CN-107299072-A | Engineering bacterium and application thereof | 江南大学 | 2017-10-27 | — | — | CN | claimed |
| CN-107109396-A | Methods for fine-tuning gene expression using synthetically regulated sRNA | 韩国科学技术院 | 2017-08-29 | — | — | CN | claimed |
| US-20170175164-A1 | L-2-HYDROXYGLUTARATE AND STRESS INDUCED METABOLISM | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-06-22 | — | — | US | claimed |
| WO-2017076602-A1 | METHODS OF T-LYMPHOCYTE EXPANSION | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2017-05-11 | — | — | WO | claimed |
| EP-3122893-A1 | L-2-HYDROXYGLUTARATE AND STRESS INDUCED METABOLISM | Memorial Sloan Kettering Cancer Center (US) | 2017-02-01 | — | — | EP | claimed |
| WO-2015148950-A1 | L-2-HYDROXYGLUTARATE AND STRESS INDUCED METABOLISM | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2015-10-01 | — | — | WO | claimed |
| EP-1326993-B1 | PRODUCTION OF ALPHA-HYDROXY-CARBOXYLIC ACIDS USING A COUPLED ENZYME SYSTEM | EXCELSYN MOLECULAR DEV LTD (GB) | 2007-05-23 | — | — | EP | claimed |
| US-20040053382-A1 | Production of alpha-hydroxy-carboxylic acids using a coupled enzyme system | EXCELSYN MOLECULAR DEVELOPMENT LIMITED (GB) | 2004-03-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250000903-A1 | EXPANSION PROCESSES AND AGENTS FOR TUMOR INFILTRATING LYMPHOCYTES | NFATC1, MKI67, ICOS | TET2 6/4885KDM4A 105/4885KDM4C 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.