Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27994085 | 0.84 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL9480145 | 0.81 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL9480206 | 0.81 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL9480621 | 0.81 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL9481033 | 0.81 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL9480566 | 0.81 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL9482861 | 0.81 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL9481807 | 0.81 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Acrylic Acid Ethyl Ester SCHEMBL9485647 | 0.81 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB | |
| Dymanthine SCHEMBL9482231 | 0.81 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077928-A1 | Polymerization using a diallylamine and a compound comprising a macromolecular chain comprising units derived from this amine | RHODIA OPERATIONS (FR) | 2012-03-29 | — | — | US | disclosed |
| US-20110130321-A1 | HEAT-SENSITIVE EMULSIONS | RHODIA OPERATIONS (FR) | 2011-06-02 | — | — | US | disclosed |
| US-20100093929-A1 | Polymerization Of Macromolecular Monomers Comprising Diallyamine Structual Units | RHODIA OPERATIONS (FR) | 2010-04-15 | — | — | US | disclosed |