Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK1 | P06870 | 2/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 8/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 7/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8648364 | 0.91 | KLK1 (0.39) | KLK1KLK5F10F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL8643480 | 0.89 | KLK1 (0.43) | KLK1KLK5F10F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL8646468 | 0.89 | KLK1 (0.43) | KLK1KLK5F10F2TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL8642843 | 0.88 | KLK1 (0.40) | KLK1KLK5F10F2TMPRSS6 | |
| SCHEMBL8643874 | 0.88 | F10 (0.39) | KLK1KLK5F10F2ITGB3 | |
| Trifluoroacetic Acid SCHEMBL8644459 | 0.87 | F10 (0.41) | KLK1KLK5F10F2TMPRSS6 | |
| Hydrochloric Acid SCHEMBL8643111 | 0.87 | F10 (0.38) | KLK1KLK5F10F2TMPRSS6 | |
| SCHEMBL8644198 | 0.86 | F10 (0.40) | KLK1KLK5F10F2ITGB3 | |
| Trifluoroacetic Acid SCHEMBL8644842 | 0.86 | KLK1 (0.40) | KLK1KLK5F10F2TMPRSS6 | |
| SCHEMBL8645969 | 0.85 | F10 (0.40) | KLK1F10F2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |