Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651383 | 1.00 | HTR1D (0.54) | HTR1DHTR1B | |
| SCHEMBL8646165 | 0.91 | HTR1D (0.54) | HTR1DHTR1B | |
| SCHEMBL8649466 | 0.91 | HTR1D (0.54) | HTR1DHTR1B | |
| SCHEMBL8647701 | 0.91 | HTR1D (0.54) | HTR1DHTR1B | |
| SCHEMBL8697299 | 0.85 | HTR1D (0.67) | HTR1DHTR1B | |
| SCHEMBL8696689 | 0.76 | HTR1D (0.67) | HTR1DHTR1B | |
| SCHEMBL8651415 | 0.75 | HTR1D (0.65) | HTR1DHTR1B | |
| SCHEMBL8699507 | 0.75 | HTR1D (0.65) | HTR1DHTR1B | |
| SCHEMBL8651228 | 0.75 | HTR1D (0.65) | HTR1DHTR1B | |
| SCHEMBL8643798 | 0.72 | HTR1D (0.66) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854268-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARP & DOHME, LTD. (GB) | 1998-12-29 | — | — | US | claimed |
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | claimed |
| US-5854268-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARP & DOHME, LTD. (GB) | 1998-12-29 | — | — | US | disclosed |