Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27406050 | 1.00 | DPP4 (0.33) | DPP4AAK1HDAC6HDAC1HDAC2 | |
| SCHEMBL7176203 | 0.82 | DPP4 (0.51) | DPP4AAK1HDAC6HDAC1HDAC2 | |
| SCHEMBL28163245 | 0.82 | DPP4 (0.33) | DPP4AAK1HDAC6HDAC1HDAC2 | |
| SCHEMBL38666150 | 0.82 | DPP4 (0.33) | DPP4AAK1HDAC6HDAC1HDAC2 | |
| SCHEMBL3244669 | 0.82 | DPP4 (0.33) | DPP4AAK1HDAC6HDAC1HDAC2 | |
| SCHEMBL5345861 | 0.79 | AAK1 (0.35) | AAK1HDAC6HDAC1HDAC2MMP13 | |
| SCHEMBL643632 | 0.77 | AAK1 (0.35) | AAK1HDAC6HDAC1HDAC2MMP13 | |
| SCHEMBL27492980 | 0.77 | AAK1 (0.39) | AAK1HDAC6HDAC1HDAC2MMP13 | |
| SCHEMBL21964901 | 0.75 | CA1 (0.35) | DPP4AAK1HDAC6HDAC1HDAC2 | |
| SCHEMBL4794923 | 0.75 | AAK1 (0.34) | AAK1HDAC6HDAC1HDAC2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |