SCHEMBL8644672

SCHEMBL8644672

FC(F)OC(F)(Cl)C(F)(F)Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8939813 0.77
SCHEMBL11544926 0.75
SCHEMBL30524278 0.75 MEN1 (0.33) MEN1KMT2A
SCHEMBL11882348 0.73
SCHEMBL8939820 0.73
SCHEMBL11847619 0.71 MEN1 (0.31) MEN1KMT2A
SCHEMBL11837439 0.69 MEN1 (0.33) MEN1KMT2A
SCHEMBL11254526 0.69 MEN1 (0.33) MEN1KMT2A
SCHEMBL9021413 0.69 MEN1 (0.33) MEN1KMT2A
SCHEMBL3505985 0.69 MEN1 (0.33) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0857773-A2 Compositions including 1,1,1,2,3,4,4,5,5,5-decafluoropentane E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-08-12 EP disclosed
EP-0830436-A1 REFRIGERANTS BASED ON HYDROFLUOROETHER OF FLUOROETHER E.I. DU PONT DE NEMOURS & CO. (INC.) (US) 1998-03-25 EP disclosed
US-5730894-A OF OCTAFLUOROBUTANE AND A FLUOROETHER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-24 US disclosed
WO-1997039081-A1 1,1,2,2,3,3,4,4-OCTAFLUOROBUTANE COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-10-23 WO disclosed
WO-1996040834-A1 REFRIGERANTS BASED ON HYDROFLUOROETHER OF FLUOROETHER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-12-19 WO disclosed
US-5578137-A REFRIGERANTS, CLEANING CIRCUIT BOARDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-11-26 US disclosed
EP-0716674-A1 COMPOSITIONS INCLUDING 1,1,1,2,3,4,4,5,5,5-DECAFLUOROPENTANE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-06-19 EP disclosed
WO-1995006693-A1 COMPOSITIONS INCLUDING 1,1,1,2,3,4,4,5,5,5-DECAFLUOROPENTANE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-09 WO disclosed
US-4149018-A Compound CHCl2 -O-CHF-CHF2 IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-04-10 US disclosed