Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641582 | 0.90 | TTR (0.63) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL8646189 | 0.88 | TTR (0.63) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL8644035 | 0.86 | TTR (0.69) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL8646851 | 0.86 | TTR (0.65) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL3332430 | 0.85 | TTR (0.61) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL5605274 | 0.85 | TTR (0.60) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL5605812 | 0.83 | TTR (0.61) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13777334 | 0.81 | TTR (0.67) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL13109322 | 0.81 | TTR (0.67) | TTRCYP2C9USP2LMNATBXA2R | |
| SCHEMBL10116869 | 0.81 | TTR (0.70) | TTRCYP2C9USP2LMNATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5844696-A | Nitric esters from derivatives of 2-(2,6-dihalophenylamino) phenylacetoxyacetic acid and their preparation process | PRODES, S.A. (ES) | 1998-12-01 | — | — | US | disclosed |
| EP-0738706-B1 | Nitric esters of 2-(2,6-dihalophenylamino) phenylacetoxyacetic acid derivatives and their preparation process | PRODES SA (ES) | 1998-10-07 | — | — | EP | disclosed |
| EP-0738706-A1 | Nitric esters of 2-(2,6-dihalophenylamino) phenylacetoxyacetic acid derivatives and their preparation process | PRODES, S.A. (ES) | 1996-10-23 | — | — | EP | disclosed |