SCHEMBL8645211

SCHEMBL8645211

C=CC(=O)OCCO.C=COCCCS(=O)(=O)O.[NaH]

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.56
ALDH1A1 P00352 4/20 0.43
CYP3A4 P08684 2/20 0.43
HPGD P15428 1/20 0.40
TP53 P04637 3/20 0.40
HIF1A Q16665 3/20 0.40
HSD17B10 Q99714 1/20 0.40
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
THRB P10828 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL474181 0.84 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL14882 0.82 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9188783 0.82 APP (0.39)
SCHEMBL316981 0.81 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2457988 0.81 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
Potassium SCHEMBL29895343 0.81 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL730023 0.80 APP (0.41)
SCHEMBL9640128 0.79 TSHR (0.64) TSHRALDH1A1CYP3A4HPGDTP53
Sulfuric Acid SCHEMBL1683520 0.79 TSHR (0.83) TSHRALDH1A1CYP3A4HPGDTP53
Acrylic Acid SCHEMBL17666860 0.78 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5854318-A Cement additive, method for producing the same, and cement composition NIPPON SHOKUBAI KAGAKU KOGYO CO, LTD. (JP) 1998-12-29 US disclosed
US-5476885-A Crosslinked polymer which cleaves in alkaline medium to form water soluble polymer NIPPON SHOKUBAI CO., LTD. (JP) 1995-12-19 US disclosed
EP-0448717-A1 CEMENT ADMIXTURE, PRODUCTION THEREOF, AND CEMENT COMPOSITION NIPPON SHOKUBAI CO., LTD. (JP) 1991-10-02 EP disclosed