Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | ARG2 | P78540 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26912729 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1AALDH1A1ARG1ARG2 | |
| SCHEMBL8814083 | 0.71 | POLB (0.48) | SMN1; SMN2MMERAB9AACEPOLB | |
| SCHEMBL11035726 | 0.71 | SMN1; SMN2 (0.56) | SMN1; SMN2HIF1AALDH1A1ARG1ARG2 | |
| SCHEMBL7224170 | 0.71 | MAPT (0.45) | HIF1AGAAMAPTMMECPA1 | |
| SCHEMBL31604212 | 0.71 | GAA (0.41) | SMN1; SMN2HIF1AGAAMAPTMME | |
| SCHEMBL25221839 | 0.71 | GAA (0.52) | GAAMAPTMMECPA1CPB1 | |
| SCHEMBL30166762 | 0.70 | GNPAT (0.38) | NPSR1ALDH1A1NAALAD2 | |
| SCHEMBL9618909 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2HIF1AGAAMAPTMME | |
| SCHEMBL60484 | 0.69 | GAA (0.62) | GAAMAPTMMECPA1CPB1 | |
| SCHEMBL31267566 | 0.69 | GAA (0.62) | GAAMAPTMMECPA1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5820881-A | BIOLOGICALLY AND CHEMICALLY ACTIVE AGENTS, ENZYME INHIBITOR, EXCIPIENT, DILUENT, LUBRICANT, DISINTEGRANT, PLASTICIZER COLORANT AND DOSAGE VEHICLE | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-10-13 | — | — | US | disclosed |