Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814122 | 0.85 | TYMP (0.43) | TYMPNPC1HPGDMAPK1HTT | |
| SCHEMBL18602092 | 0.80 | TYMP (0.41) | TYMPNPC1HPGDMAPK1HTT | |
| SCHEMBL4633204 | 0.79 | NPC1 (0.48) | TYMPNPC1HPGDMAPK1HTT | |
| SCHEMBL5586732 | 0.78 | HPGD (0.45) | TYMPNPC1HPGDMAPK1HTT | |
| SCHEMBL5589634 | 0.78 | HPGD (0.41) | TYMPNPC1HPGDMAPK1HTT | |
| SCHEMBL5586631 | 0.78 | HPGD (0.41) | TYMPNPC1HPGDMAPK1HTT | |
| SCHEMBL27951398 | 0.77 | DPP4 (0.37) | TYMPHPGDTSHRLMNATDP1 | |
| SCHEMBL11781693 | 0.76 | TYMP (0.38) | TYMPNPC1HPGDMAPK1HTT | |
| SCHEMBL5589567 | 0.75 | HPGD (0.42) | TYMPNPC1HPGDMAPK1HTT | |
| SCHEMBL10446044 | 0.75 | HTT (0.42) | TYMPNPC1HPGDMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513730-B1 | Process for preparing arylene sulfide polymers | PHILLIPS PETROLEUM CO (US) | 1998-08-26 | — | — | EP | disclosed |
| EP-0487103-B1 | Process for preparing arylene sulfide polymers | PHILLIPS PETROLEUM CO (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5364928-A | Reaction of sulfide, cyclic amide and dihaloaromatic with separation by addition of aqueous alkali metal carboxylate | PHILLIPS PETROLEUM COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| US-5239050-A | PROCESS FOR PREPARING ARYLENE SULFIDE POLYMER WITH ADDITION OF AQUEOUS ALKALI METAL CARBOXYLATE PRIOR TO TERMINATION OF POLYMERIZATION | PHILLIPS PETROLEUM COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0534359-A1 | Process for preparing arylene sulfide polymers | PHILLIPS PETROLEUM COMPANY (US) | 1993-03-31 | — | — | EP | disclosed |
| US-5175243-A | Reaction of a sulfur source and a dihalobenzene in cyclic amide | PHILLIPS PETROLEUM COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0513730-A2 | Process for preparing arylene sulfide polymers | PHILLIPS PETROLEUM COMPANY (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5159056-A | Preparation of arylene sulfide polymer in the presence of titanium dioxide | PHILLIPS PETROLEUM COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0487103-A1 | Process for preparing arylene sulfide polymers | PHILLIPS PETROLEUM COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |
| EP-0486014-A1 | Process for preparing arylene sulfide polymers | PHILLIPS PETROLEUM COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| US-5115093-A | Reaction of a dihaloaromatic with sulfide in the presence of an olefin to control molecular weight and for extrusion | PHILLIPS PETROLEUM COMPANY (US) | 1992-05-19 | — | — | US | disclosed |
| US-5064936-A | Process for preparing high extrusion rate arylene sulfide polymers | PHILLIPS PETROLEUM COMPANY (US) | 1991-11-12 | — | — | US | disclosed |
| US-4882416-A | FILTRATION, HEAT RESISTANCE, POLYPHENYLENE SULFIDE | PHILLIPS PETROLEUM COMPANY (US) | 1989-11-21 | — | — | US | disclosed |
| EP-0280271-A2 | Arylene sulfide polymers | PHILLIPS PETROLEUM COMPANY (US) | 1988-08-31 | — | — | EP | disclosed |