Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 20/20 | 0.66 |
| ▸ | HTR1B | P28222 | 20/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651228 | 0.92 | HTR1D (0.65) | HTR1DHTR1B | |
| SCHEMBL8651415 | 0.92 | HTR1D (0.65) | HTR1DHTR1B | |
| SCHEMBL8699507 | 0.92 | HTR1D (0.65) | HTR1DHTR1B | |
| SCHEMBL8645005 | 0.89 | HTR1D (0.67) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8643497 | 0.89 | HTR1D (0.68) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8649135 | 0.83 | HTR1D (0.68) | HTR1DHTR1B | |
| SCHEMBL8697299 | 0.83 | HTR1D (0.67) | HTR1DHTR1B | |
| SCHEMBL8696689 | 0.83 | HTR1D (0.67) | HTR1DHTR1B | |
| SCHEMBL8649173 | 0.83 | HTR1D (0.66) | HTR1DHTR1B | |
| SCHEMBL8643798 | 0.81 | HTR1D (0.66) | HTR1DHTR1BHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854268-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARP & DOHME, LTD. (GB) | 1998-12-29 | — | — | US | claimed |
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | claimed |
| US-5854268-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARP & DOHME, LTD. (GB) | 1998-12-29 | — | — | US | disclosed |
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | disclosed |