Methacrylic Acid

Methacrylic Acid

SCHEMBL8645938

C=C(C)C(=O)O.C=C(C)C(=O)OCCCC.C=C(C)C(=O)OCCO.C=C(C)C(=O)OCCOC(=O)C(=C)C

nearest known ligand 0.64

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.64
THRB P10828 1/20 0.51
ALDH1A1 P00352 1/20 0.46
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ACHE P22303 7/20 0.41
HPGD P15428 1/20 0.41
ATM Q13315 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
MGLL Q99685 1/20 0.35
NAAA Q02083 1/20 0.34
DGKA P23743 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL7253551 0.98 TSHR (0.66) TSHRTHRBALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL10885386 0.94 TSHR (0.60) TSHRTHRBALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL28463451 0.93 TSHR (0.68) TSHRTHRBALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL6235110 0.93 TSHR (0.68) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1004833 0.93 TSHR (0.72) TSHRTHRBALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL8153055 0.92 TSHR (0.58) TSHRTHRBALDH1A1POLBAPEX1
Triethylene Glycol SCHEMBL27622849 0.92 TSHR (0.58) TSHRTHRBALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL8427966 0.91 TSHR (0.75) TSHRTHRBALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL8406971 0.91 TSHR (0.75) TSHRTHRBALDH1A1POLBAPEX1
Methacrylic Acid SCHEMBL462262 0.91 TSHR (0.75) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5849449-A Electrostatographic developer having toner particles containing polymers of (2-cyanoacetamido)phenyl acrylates polymers EASTMAN KODAK COMPANY (US) 1998-12-15 US disclosed