SCHEMBL8646274

SCHEMBL8646274

O=CCCCCCCCC(=O)NCCCCCC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 10/20 0.67
KDM4E B2RXH2 1/20 0.57
PRMT1 Q99873 1/20 0.55
FAAH O00519 2/20 0.53
CNR1 P21554 2/20 0.53
CNR2 P34972 2/20 0.53
ADRA1A P35348 1/20 0.52
SLC6A5 Q9Y345 3/20 0.51
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
KMT2A Q03164 1/20 0.51
LMNA P02545 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15773253 1.00 EPHX2 (0.67) EPHX2KDM4EPRMT1FAAHCNR1
SCHEMBL18973044 0.95 EPHX2 (0.59) EPHX2KDM4EPRMT1FAAHCNR1
SCHEMBL18973109 0.95 EPHX2 (0.59) EPHX2KDM4EPRMT1FAAHCNR1
SCHEMBL19752293 0.95 EPHX2 (0.59) EPHX2KDM4EPRMT1FAAHCNR1
SCHEMBL18972946 0.95 EPHX2 (0.59) EPHX2KDM4EPRMT1FAAHCNR1
SCHEMBL19752295 0.93 EPHX2 (0.58) EPHX2KDM4EPRMT1FAAHCNR1
SCHEMBL14946562 0.93 EPHX2 (0.62) EPHX2KDM4EPRMT1FAAHCNR1
SCHEMBL18973108 0.93 EPHX2 (0.58) EPHX2KDM4EPRMT1FAAHCNR1
SCHEMBL21387243 0.93 EPHX2 (0.57) EPHX2KDM4EPRMT1FAAHCNR1
SCHEMBL17776037 0.93 EPHX2 (0.56) EPHX2KDM4EFAAHCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859756-A1 PREPARATION OF AMIDO ESTER COMPOUNDS EASTMAN CHEMICAL COMPANY (US) 1998-08-26 EP disclosed
WO-1996039378-A1 PREPARATION OF AMIDO ESTER COMPOUNDS EASTMAN CHEMICAL COMPANY (US) 1996-12-12 WO disclosed