Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | IDE | P14735 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HLCS | P50747 | 6/20 | 0.52 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22190207 | 0.89 | TDP1 (0.64) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL28780247 | 0.88 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL28346778 | 0.88 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL28119479 | 0.85 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21114407 | 0.85 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL28283183 | 0.85 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21176811 | 0.85 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL30058455 | 0.84 | TDP1 (0.64) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL28329063 | 0.84 | TDP1 (0.57) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL22265330 | 0.84 | TDP1 (0.79) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627939-A1 | CONJUGATES OF BIOTIN AND DEFEROXAMINE FOR RADIOIMMUNOIMAGING AND RADIOIMMUNOTHERAPY | THE UNIVERSITY OF ROCHESTER (US) | 1994-12-14 | — | — | EP | claimed |
| EP-3088004-B1 | CYSTEINE ENGINEERED ANTIBODIES AND CONJUGATES | GENENTECH INC (US) | 2018-03-28 | — | — | EP | disclosed |
| US-5807879-A | Biotinidase-resistant biotinylated compound and methods of use thereof | UNIVERSITY OF ROCHESTER (US) | 1998-09-15 | — | — | US | disclosed |