SCHEMBL864699

SCHEMBL864699

[CH]=CCCCF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL865454 0.90
SCHEMBL20474566 0.87
SCHEMBL865995 0.87
SCHEMBL714487 0.77
SCHEMBL3499333 0.76
SCHEMBL1541496 0.72
SCHEMBL535034 0.71
SCHEMBL28999179 0.69
SCHEMBL5184371 0.69
SCHEMBL1470430 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022115521-A1 (HETEO)ARYL SUBSTITUTED PYRROLO-, PYRAZOLO- AND TRIAZOLOPYRIDAZINE DERIVATES AS MAT2A INHIBITORS SERVIER PHARMACEUTICALS, LLC (US) 2022-06-02 WO claimed
WO-2023174773-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2023-09-21 WO disclosed
US-20220169654-A1 New Organic Compounds SERVIER PHARMACEUTICALS LLC (US) 2022-06-02 US disclosed
WO-2022115521-A1 (HETEO)ARYL SUBSTITUTED PYRROLO-, PYRAZOLO- AND TRIAZOLOPYRIDAZINE DERIVATES AS MAT2A INHIBITORS SERVIER PHARMACEUTICALS, LLC (US) 2022-06-02 WO disclosed
CN-114391192-A Composite polymer electrolyte membrane, electrolyte membrane with catalyst layer, membrane electrode assembly, and solid polymer fuel cell 东丽株式会社 2022-04-22 CN disclosed
CN-104649916-B Photocrosslinkable materials 罗利克有限公司 2020-12-01 CN disclosed
CN-107206822-B Recording materials and recording sheet 日本曹达株式会社 2019-11-26 CN disclosed
CN-105198861-B 6- acyl group -1,2,4- triazine -3,5- derovatives and herbicide FMC公司 2019-11-22 CN disclosed
CN-107245023-B A kind of selectivity deoxofluorination reagent and method 中国科学院上海有机化学研究所 2019-08-16 CN disclosed
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group ROLIC AG (CH) 2019-02-19 US disclosed
US-5538981-A 5-HYDROXYTRYPTAMINE RECEPTOR ANTAGONIST ACTIVITY ELI LILLY AND COMPANY (US) 1996-07-23 US disclosed
US-5538980-A CENTRAL NERVOUS SYSTEM ELI LILLY AND COMPANY (US) 1996-07-23 US disclosed
US-5488053-A Tetrahydro-pyrido-indole ELI LILLY AND COMPANY (US) 1996-01-30 US disclosed
EP-0679707-A1 Liquid crystalline compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1995-11-02 EP disclosed
WO-1994024132-A1 TETRAHYDRO-PYRIDO-INDOLE ELI LILLY AND COMPANY (US) 1994-10-27 WO disclosed
EP-0620223-A2 Tetrahydro-pyrido-indole ELI LILLY AND COMPANY (US) 1994-10-19 EP disclosed
US-5300645-A Condensation of cycloalkyl-, phenyl- or naphthylpyrrole ethylamines with a 2-oxazolidinone to get antiserotonine agent ELI LILLY AND COMPANY (US) 1994-04-05 US disclosed
EP-0192242-B1 SUBSTITUTED AMINOPHENYLUREA DERIVATIVES TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-11-07 EP disclosed
US-4803223-A ANTITUMOR AGENTS TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1989-02-07 US disclosed
EP-0192242-A1 Substituted aminophenylurea derivatives TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-08-27 EP disclosed