Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650134 | 1.00 | SSTR4 (0.47) | SSTR4SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL8647230 | 1.00 | SSTR4 (0.47) | SSTR4SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL4749429 | 0.82 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL4488371 | 0.82 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| SCHEMBL21564402 | 0.77 | KDM1A (0.45) | SSTR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8651321 | 0.77 | KDM1A (0.45) | SSTR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4447151 | 0.77 | KDM1A (0.45) | SSTR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3134201 | 0.77 | KDM1A (0.45) | SSTR4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5668614 | 0.77 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6KCNH2 | |
| Hydrochloric Acid SCHEMBL518193 | 0.76 | KDM1A (0.44) | SSTR4SLC6A2SLC6A4SLC6A3TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837715-A | 3-fluoro-4-aminopiperidine derivatives as 5-HT receptor agonists | MERCK SHARP & DOHME LTD. (GB) | 1998-11-17 | — | — | US | disclosed |