Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 20/20 | 0.79 |
| ▸ | HTR1B | P28222 | 19/20 | 0.79 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647369 | 1.00 | HTR1D (0.79) | HTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8649602 | 0.93 | HTR1D (0.73) | HTR1DHTR1B | |
| SCHEMBL8649604 | 0.88 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8647188 | 0.88 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8647191 | 0.88 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL4352154 | 0.87 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8650658 | 0.85 | HTR1D (0.78) | HTR1DHTR1B | |
| SCHEMBL8650661 | 0.85 | HTR1D (0.78) | HTR1DHTR1B | |
| SCHEMBL8646078 | 0.83 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8646075 | 0.83 | HTR1D (1.00) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837715-A | 3-fluoro-4-aminopiperidine derivatives as 5-HT receptor agonists | MERCK SHARP & DOHME LTD. (GB) | 1998-11-17 | — | — | US | claimed |
| US-5837715-A | 3-fluoro-4-aminopiperidine derivatives as 5-HT receptor agonists | MERCK SHARP & DOHME LTD. (GB) | 1998-11-17 | — | — | US | disclosed |