Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137130 | 1.00 | MAPT (0.43) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL5160091 | 1.00 | MAPT (0.43) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL9233916 | 1.00 | MAPT (0.43) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL6587420 | 1.00 | MAPT (0.43) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL8648044 | 1.00 | MAPT (0.43) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL8646134 | 1.00 | MAPT (0.43) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL5154559 | 1.00 | MAPT (0.43) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL8647947 | 1.00 | MAPT (0.43) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL8650122 | 1.00 | MAPT (0.43) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL1410679 | 1.00 | MAPT (0.43) | MAPTGPR84FDPSFFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604957-B1 | 2-Amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-09 | — | — | EP | disclosed |
| US-5478809-A | Blood disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| US-5478808-A | Blood disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0638588-A1 | Derivatives of 6,7-Dihydroxy-4-thiaheptonic acid and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| EP-0604945-A1 | TAN-1511, its derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |
| EP-0604957-A1 | 2-Amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |