SCHEMBL8647997

SCHEMBL8647997

OC1(Br)C=Nc2cccc(Cl)c21

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
PDK2 Q15119 1/20 0.32
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dichlorobenzene SCHEMBL10593125 0.56
1,2-Dichlorobenzene SCHEMBL1155123 0.56 TSHR (1.00) TSHRLMNACYP1A2CYP2A6
1,2-Dichlorobenzene SCHEMBL5190 0.56
1,2-Dichlorobenzene SCHEMBL29350623 0.56
SCHEMBL4821733 0.54 CYP1A2 (0.35) TSHRLMNACYP1A2CYP2A6
SCHEMBL5189360 0.54 CYP1A2 (0.39) TSHRLMNAPDK2CYP1A2CYP2A6
1,2-Dichlorobenzene SCHEMBL11283617 0.53 TSHR (0.91) TSHRLMNACYP1A2CYP2A6
1,2-Dichlorobenzene SCHEMBL11889383 0.53 TSHR (0.91) TSHRLMNACYP1A2CYP2A6
1,2-Dichlorobenzene SCHEMBL9662162 0.53
1,2-Dichlorobenzene SCHEMBL16793414 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150140573-A1 ASSAYS FOR DETECTING GLUCOSIDASE ACTIVITY MEGAZYME INTERNATIONAL IRELAND (IE) 2015-05-21 US disclosed
WO-2013185771-A1 ASSAYS FOR DETECTING GLUCOSIDASE ACTIVITY CARLSBERG A/S, CARLSBERG FORSKNINGSCENTER (DK) 2013-12-19 WO disclosed
EP-0530850-B1 Process for producing a modified oligosaccharide WAKO PURE CHEM IND LTD (JP) 1998-09-09 EP disclosed
EP-0557021-B1 Oligosaccharide derivatives suitable for alpha-amylase determination WAKO PURE CHEM IND LTD (JP) 1997-12-17 EP disclosed
US-5393876-A Process for producing maltooligosaccharide derivatives WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1995-02-28 US disclosed
US-5350678-A Method of differential assay for α-amylase isozymes and a kit for the same WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1994-09-27 US disclosed
US-5319078-A α-amylase assay using modified oligosaccharide and process for producing said modified oligosaccharide WAKO PURE CHEMICAL INDUSTRIES, INC. (JP) 1994-06-07 US disclosed
US-5319076-A Oligosaccharide derivatives suitable for α-amylase determination WAKO PURE CHEMICAL INDUSTRIES, INC. (JP) 1994-06-07 US disclosed
US-5300634-A Process for producing maltooligosaccharide derivative WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-05 US disclosed
EP-0252525-B1 Alpha-amylase assay using modified oligosaccharide and process for producing said modified oligosaccharide WAKO PURE CHEM IND LTD (JP) 1993-11-10 EP disclosed
EP-0566366-A2 Process for producing maltooligosaccharide derivative WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1993-10-20 EP disclosed
EP-0557021-A2 Oligosaccharide derivatives suitable for alpha-amylase determination WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1993-08-25 EP disclosed
EP-0530850-A2 Process for producing a modified oligosaccharide WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-10 EP disclosed
US-5192666-A α-amylase assay using modified oligosaccharide and process for producing said modified oligosaccharide WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-09 US disclosed
EP-0512808-A1 Process for producing maltooligosaccharide derivative WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1992-11-11 EP disclosed
EP-0260414-B1 METHOD OF DIFFERENTIAL ASSAY FOR ALPHA-AMYLASE ISOZYMES AND A KIT FOR THE SAME WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-04-15 EP disclosed
EP-0260414-A2 Method of differential assay for alpha-amylase isozymes and a kit for the same WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1988-03-23 EP disclosed
EP-0252525-A2 Alpha-amylase assay using modified oligosaccharide and process for producing said modified oligosaccharide WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1988-01-13 EP disclosed