Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.30 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL821221 | 0.93 | TSHR (0.46) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL6033 | 0.93 | TSHR (0.46) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL7874985 | 0.93 | TSHR (0.46) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL27935253 | 0.90 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL10708119 | 0.90 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL27868357 | 0.90 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL8651503 | 0.90 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL10417672 | 0.90 | TSHR (0.38) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL7631534 | 0.89 | TSHR (0.43) | TSHRLMNATDP1THRBALDH1A1 | |
| SCHEMBL2497998 | 0.89 | TSHR (0.43) | TSHRLMNATDP1THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516982-B1 | Process for producing a heterocyclic tertiary amine | NISSAN CHEMICAL IND LTD (JP) | 1998-09-16 | — | — | EP | disclosed |
| US-5283341-A | Catalytic alkylation | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0516982-A1 | Process for producing a heterocyclic tertiary amine | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |