Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK1 | P19367 | 2/20 | 0.61 |
| ▸ | HK2 | P52789 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 5/20 | 0.61 |
| ▸ | CA2 | P00918 | 5/20 | 0.61 |
| ▸ | CA9 | Q16790 | 5/20 | 0.61 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.53 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.53 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.53 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15514659 | 0.89 | SLC6A2 (0.49) | HK1HK2CA1CA2CA9 | |
| SCHEMBL8652701 | 0.88 | SLC6A2 (0.48) | HK1HK2CA1CA2CA9 | |
| SCHEMBL14520980 | 0.87 | MAPK1 (0.58) | — | |
| SCHEMBL20643560 | 0.87 | MAPK1 (0.58) | — | |
| SCHEMBL21097246 | 0.87 | MAPK1 (0.58) | — | |
| SCHEMBL14544300 | 0.87 | MAPK1 (0.58) | — | |
| SCHEMBL13031052 | 0.87 | MAPK1 (0.58) | — | |
| SCHEMBL542627 | 0.87 | MAPK1 (0.58) | — | |
| SCHEMBL7150940 | 0.87 | MAPK1 (0.58) | — | |
| SCHEMBL5841792 | 0.87 | MAPK1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767268-A | TREATMENT OF DISORDERS CHARACTERIZED BY EXCESSIVE OR DESTRUCTIVE PROLIFERATION OF SMOOTH MUSCLE CELLS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0741139-A1 | Sulphuric acid esters of amino sugars | F. HOFFMANN-LA ROCHE AG (CH) | 1996-11-06 | — | — | EP | disclosed |