Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275879 | 1.00 | TLR2 (0.62) | TLR2 | |
| SCHEMBL9277173 | 1.00 | TLR2 (0.62) | TLR2 | |
| SCHEMBL9273276 | 0.97 | TLR2 (0.65) | TLR2 | |
| SCHEMBL9273194 | 0.97 | TLR2 (0.65) | TLR2 | |
| SCHEMBL9276639 | 0.97 | TLR2 (0.65) | TLR2 | |
| SCHEMBL8650135 | 0.97 | TLR2 (0.65) | TLR2 | |
| SCHEMBL9275653 | 0.93 | TLR2 (0.57) | TLR2 | |
| SCHEMBL9266379 | 0.93 | TLR2 (0.57) | TLR2 | |
| SCHEMBL9266482 | 0.93 | TLR2 (0.57) | TLR2 | |
| SCHEMBL9273414 | 0.93 | TLR2 (0.57) | TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604957-B1 | 2-Amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-09 | — | — | EP | claimed |
| US-5478808-A | Blood disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | claimed |
| EP-0604957-A1 | 2-Amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-06 | — | — | EP | claimed |
| EP-0604957-B1 | 2-Amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-09-09 | — | — | EP | disclosed |
| US-5478808-A | Blood disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0604957-A1 | 2-Amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |