Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8650259

C=CCc1cccc2ccccc12.N

nearest known ligand 0.59

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
CYP2C19 P33261 2/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2D6 P10635 2/20 0.47
GABRA1 P14867 1/20 0.47
GABRB2 P47870 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
HPGD P15428 3/20 0.44
HTT P42858 1/20 0.44
ACP3 P15309 1/20 0.44
MEN1 O00255 3/20 0.42
ALDH1A1 P00352 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 2/20 0.42
GAA P10253 1/20 0.42
GFER P55789 1/20 0.42
KDM4E B2RXH2 1/20 0.42
POLB P06746 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30083984 0.98 CYP1A2 (0.52) CYP1A2CYP2C19CYP2C9CYP2D6GABRA1
SCHEMBL25106 0.98 CYP1A2 (0.52) CYP1A2CYP2C19CYP2C9CYP2D6GABRA1
Charcoal, Activated SCHEMBL10996447 0.96 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6GABRA1
SCHEMBL249218 0.96 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6GABRA1
Potassium SCHEMBL1617563 0.96 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6GABRA1
SCHEMBL11817244 0.96 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6GABRA1
SCHEMBL1617561 0.96 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6GABRA1
SCHEMBL249217 0.96 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6GABRA1
Water SCHEMBL11405805 0.96 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6GABRA1
SCHEMBL29253693 0.96 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0720427-B1 WATER-DISPERSIBLE GRANULAR AGRICULTURAL COMPOSITIONS MADE BY HEAT EXTRUSION DU PONT (US) 1998-06-24 EP disclosed
US-5714157-A COMPRISING A PESTICIDE, A BASE, UREA AND AN UREA MODIFIER; HIGH-SPEED DISINTEGRATION; SHELF LIFE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-02-03 US disclosed
EP-0720427-A1 WATER-DISPERSIBLE GRANULAR AGRICULTURAL COMPOSITIONS MADE BY HEAT EXTRUSION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-10 EP disclosed
WO-1995008265-A1 WATER-DISPERSIBLE GRANULAR AGRICULTURAL COMPOSITIONS MADE BY HEAT EXTRUSION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-30 WO disclosed
US-3950277-A LIPASE ENZYME AND ACTIVATORS, ALKYLNAPHTHALENE SULFONATE THE PROCTER & GAMBLE COMPANY (US) 1976-04-13 US disclosed