Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650463 | 1.00 | SRD5A2 (0.53) | SRD5A2SRD5A1AR | |
| SCHEMBL8648191 | 0.85 | SRD5A1 (0.52) | SRD5A2SRD5A1AR | |
| SCHEMBL8648194 | 0.85 | SRD5A1 (0.52) | SRD5A2SRD5A1AR | |
| SCHEMBL5682764 | 0.81 | SRD5A2 (0.64) | SRD5A2SRD5A1AR | |
| SCHEMBL4269548 | 0.81 | SRD5A2 (0.64) | SRD5A2SRD5A1AR | |
| SCHEMBL4278292 | 0.81 | SRD5A2 (0.64) | SRD5A2SRD5A1AR | |
| SCHEMBL4269554 | 0.81 | SRD5A2 (0.64) | SRD5A2SRD5A1AR | |
| SCHEMBL8650910 | 0.80 | SRD5A2 (0.53) | SRD5A2SRD5A1AR | |
| SCHEMBL8650908 | 0.80 | SRD5A2 (0.53) | SRD5A2SRD5A1AR | |
| SCHEMBL8650574 | 0.79 | SRD5A1 (0.46) | SRD5A2SRD5A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700291-B1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO INC (US) | 1998-09-16 | — | — | EP | claimed |
| WO-1994020104-A1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO, INC. (US) | 1994-09-15 | — | — | WO | claimed |
| EP-0700291-B1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0700291-A4 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO INC (US) | 1996-07-03 | — | — | EP | disclosed |
| EP-0700291-A1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO. INC. (US) | 1996-03-13 | — | — | EP | disclosed |
| US-5359071-A | Selective antagonist of testosterone 5-alpha-reductase 1 | MERCK & CO., INC. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994020104-A1 | 15-SUBSTITUTED 4-AZASTEROIDS | MERCK & CO, INC. (US) | 1994-09-15 | — | — | WO | disclosed |