Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650606 | 1.00 | MEN1 (0.31) | MEN1KMT2ACYP3A4CYP2C8CYP2D6 | |
| SCHEMBL8648095 | 0.92 | CYP2C9 (0.35) | MEN1KMT2ACYP2C9MAPT | |
| SCHEMBL8648097 | 0.92 | CYP2C9 (0.35) | MEN1KMT2ACYP2C9MAPT | |
| SCHEMBL8650295 | 0.88 | — | — | |
| SCHEMBL8650298 | 0.88 | — | — | |
| SCHEMBL10895455 | 0.83 | MEN1 (0.37) | MEN1KMT2ACYP2C9GAAMAPT | |
| SCHEMBL10895466 | 0.83 | MEN1 (0.37) | MEN1KMT2ACYP2C9GAAMAPT | |
| SCHEMBL10895268 | 0.83 | MEN1 (0.37) | MEN1KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10892109 | 0.83 | SPHK1 (0.38) | MEN1KMT2ACYP2C9GAAMAPT | |
| SCHEMBL10895264 | 0.83 | MEN1 (0.37) | MEN1KMT2ACYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800734-A | 1-fluorocyclohexene-difluorophenyl derivatives | ROLIC AG (CH) | 1998-09-01 | — | — | US | disclosed |
| EP-0736513-A1 | 1-Fluorcyclohexene-difluorphenyl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1996-10-09 | — | — | EP | disclosed |