Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650797 | 1.00 | HTT (0.56) | HTTLMNASMN1; SMN2FOLH1CTRB1 | |
| SCHEMBL8646821 | 0.98 | HTT (0.56) | HTTLMNASMN1; SMN2FOLH1CTRB1 | |
| SCHEMBL8646826 | 0.98 | HTT (0.56) | HTTLMNASMN1; SMN2FOLH1CTRB1 | |
| SCHEMBL6652290 | 0.90 | HTT (0.63) | HTTLMNASMN1; SMN2FOLH1CTRB1 | |
| SCHEMBL6649610 | 0.90 | HTT (0.63) | HTTLMNASMN1; SMN2FOLH1CTRB1 | |
| SCHEMBL1024311 | 0.86 | FOLH1 (0.61) | HTTLMNASMN1; SMN2FOLH1TGM2 | |
| SCHEMBL19295618 | 0.86 | HTT (0.60) | HTTLMNASMN1; SMN2FOLH1CTRB1 | |
| Hydrochloric Acid SCHEMBL4889200 | 0.86 | ANPEP (0.51) | HTTFOLH1SLC1A3SLC1A1SIRT2 | |
| SCHEMBL6653860 | 0.85 | FOLH1 (0.60) | HTTLMNASMN1; SMN2FOLH1TGM2 | |
| SCHEMBL7064119 | 0.85 | FOLH1 (0.60) | HTTLMNASMN1; SMN2FOLH1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849797-A | D-β-lysylmethanediamine derivatives and preparation thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-12-15 | — | — | US | disclosed |