Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654723 | 1.00 | TSHR (0.56) | TSHRHTTALOX5NAAAHDAC3 | |
| SCHEMBL8654086 | 1.00 | TSHR (0.56) | TSHRHTTALOX5NAAAHDAC3 | |
| SCHEMBL6567328 | 1.00 | TSHR (0.56) | TSHRHTTALOX5NAAAHDAC3 | |
| SCHEMBL8654054 | 0.98 | HTT (0.57) | TSHRHTTALOX5NAAAHDAC3 | |
| SCHEMBL30843288 | 0.92 | HTT (0.65) | TSHRHTTALOX5NAAAHDAC3 | |
| SCHEMBL15057855 | 0.87 | HTT (0.56) | TSHRHTTALOX5NAAAHDAC3 | |
| SCHEMBL8652703 | 0.86 | TSHR (0.53) | TSHRHTTHCRTR1HPGD | |
| SCHEMBL6565344 | 0.86 | TSHR (0.73) | TSHRHTTALOX5NAAAHCRTR1 | |
| SCHEMBL6565410 | 0.86 | TSHR (0.73) | TSHRHTTALOX5NAAAHCRTR1 | |
| SCHEMBL4443780 | 0.86 | TSHR (0.73) | TSHRHTTALOX5NAAAHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007413-A1 | SUBSTANCE P INHIBITORS IN COMBINATION WITH NMDA-BLOCKERS FOR TREATING PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 1999-02-18 | — | — | WO | disclosed |