SCHEMBL8653173

SCHEMBL8653173

CCCCC[SiH]1CCC(c2ccc(-c3cc(F)c(F)c(F)c3)c(C3CCCCC3)c2)CC1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 1/20 0.33
APP P05067 1/20 0.33
PDK2 Q15119 1/20 0.32
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8656967 0.92 CYP3A4 (0.37) CYP3A4CYP2C9APPPDK2
SCHEMBL8027624 0.91 CYP3A4 (0.37) CYP3A4CYP2C9APPPDK2
SCHEMBL8395137 0.88 CYP3A4 (0.33) CYP3A4CYP2C9APP
SCHEMBL8395134 0.88 CYP3A4 (0.33) CYP3A4CYP2C9APP
SCHEMBL8026796 0.81 CYP3A4 (0.38) CYP3A4CYP2C9APPPDK2EPHX2
SCHEMBL8441428 0.79 CYP3A4 (0.34) CYP3A4CYP2C9APP
SCHEMBL8441424 0.79 CYP3A4 (0.34) CYP3A4CYP2C9APP
SCHEMBL8027627 0.79 CYP3A4 (0.38) CYP3A4CYP2C9APP
SCHEMBL8728406 0.78 CYP3A4 (0.33) CYP3A4CYP2C9APP
SCHEMBL8728409 0.78 CYP3A4 (0.33) CYP3A4CYP2C9APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5755995-A DISAZO DYES, TRISAZO DYES AND ANTHRAQUINONE DYES WITH LIQUID CRYSTAL POLYMERS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-05-26 US disclosed