Pimelic Acid

Pimelic Acid

SCHEMBL8653232

O=C(O)CCCCCC(=O)O.Oc1cccc(O)c1

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 3/20 0.53
HDAC3 O15379 2/20 0.53
HDAC4 P56524 2/20 0.53
HDAC1 Q13547 2/20 0.53
HDAC7 Q8WUI4 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC10 Q969S8 2/20 0.53
HDAC11 Q96DB2 2/20 0.53
HDAC8 Q9BY41 2/20 0.53
HDAC9 Q9UKV0 2/20 0.53
HDAC5 Q9UQL6 2/20 0.53
MAPT P10636 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
LMNA P02545 3/20 0.52
CA12 O43570 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
ALDH1A1 P00352 1/20 0.52
CYP3A4 P08684 1/20 0.52
CA5A P35218 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azelaic Acid SCHEMBL28137606 1.00 HDAC6 (0.53) HDAC6HDAC3HDAC4HDAC1HDAC7
Resorcinol SCHEMBL8651630 1.00 HDAC6 (0.53) HDAC6HDAC3HDAC4HDAC1HDAC7
Azelaic Acid SCHEMBL8653637 1.00 HDAC6 (0.53) HDAC6HDAC3HDAC4HDAC1HDAC7
Octanedioate SCHEMBL8652135 1.00 HDAC6 (0.53) HDAC6HDAC3HDAC4HDAC1HDAC7
Resorcinol SCHEMBL8650701 1.00 HDAC6 (0.53) HDAC6HDAC3HDAC4HDAC1HDAC7
Sebacic Acid SCHEMBL3166152 1.00 HDAC6 (0.53) HDAC6HDAC3HDAC4HDAC1HDAC7
Resorcinol SCHEMBL8652804 1.00 HDAC6 (0.53) HDAC6HDAC3HDAC4HDAC1HDAC7
Resorcinol SCHEMBL8653977 1.00 HDAC6 (0.53) HDAC6HDAC3HDAC4HDAC1HDAC7
Resorcinol SCHEMBL8655659 1.00 HDAC6 (0.53) HDAC6HDAC3HDAC4HDAC1HDAC7
Sebacic Acid SCHEMBL27497118 1.00 HDAC6 (0.53) HDAC6HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7101907-A None JP disclosed
EP-0688759-B1 Alpha-resorcylic acid ester derivatives and recording materials incorporating them FUJI PHOTO FILM CO LTD (JP) 1998-10-07 EP disclosed
US-5693374-A Alpha-resorcyclic acid ester derivatives and recording materials using the same FUJI PHOTO FILM CO., LTD. (JP) 1997-12-02 US disclosed
EP-0688759-A1 Alpha-resorcylic acid ester derivatives and recording materials incorporating them FUJI PHOTO FILM CO., LTD. (JP) 1995-12-27 EP disclosed
JP-H07101907-A ALPHA-RESORCYLIC ESTER DERIVATIVE AND RECORDING MATERIAL USING THE SAME FUJI PHOTO FILM CO LTD 1995-04-18 JP disclosed