Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654017 | 0.92 | HCAR2 (0.45) | MAPTCACNA1BAPBA1TSHRSMN1; SMN2 | |
| SCHEMBL18649630 | 0.92 | HCAR2 (0.45) | MAPTCACNA1BAPBA1TSHRSMN1; SMN2 | |
| SCHEMBL466122 | 0.86 | — | — | |
| SCHEMBL28515956 | 0.84 | TSHR (0.37) | MAPTTSHRSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL1489998 | 0.80 | TSHR (0.39) | MAPTTSHRSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL1489999 | 0.78 | — | — | |
| SCHEMBL3468914 | 0.78 | — | — | |
| SCHEMBL1154368 | 0.76 | — | — | |
| SCHEMBL28370295 | 0.76 | — | — | |
| SCHEMBL5377002 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10182559-A | — | — | None | — | — | JP | disclosed |
| JP-H10182559-A | PRODUCTION OF DIALKYL OXALACETATE | AMERICAN CYANAMID CO | 1998-07-07 | — | — | JP | disclosed |