Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235575 | 0.83 | ACACB (0.58) | HSD17B10SMN1; SMN2HDAC3MAPK1ADRA1A | |
| SCHEMBL9099482 | 0.82 | ESR1 (0.55) | ESR1KCNH2SMN1; SMN2HDAC3MAPK1 | |
| SCHEMBL4462033 | 0.81 | NPC1 (0.67) | ESR1KCNH2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8420771 | 0.81 | NPC1 (0.67) | ESR1KCNH2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6679690 | 0.81 | NPC1 (0.67) | ESR1KCNH2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11235453 | 0.80 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2HDAC3MAPK1ADRA1A | |
| SCHEMBL13311943 | 0.80 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2HDAC3MAPK1ADRA1A | |
| SCHEMBL3391414 | 0.80 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2HDAC3MAPK1ADRA1A | |
| SCHEMBL8986819 | 0.80 | ESR1 (0.54) | ESR1KCNH2NPC1RAB9AACACB | |
| SCHEMBL8986825 | 0.80 | ESR1 (0.54) | ESR1KCNH2NPC1RAB9AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574782-B1 | Dual analyte immunoassay | HOFFMANN LA ROCHE (CH) | 1998-10-21 | — | — | EP | disclosed |
| EP-0574782-A2 | Dual analyte immunoassay | F. HOFFMANN-LA ROCHE AG (CH) | 1993-12-22 | — | — | EP | disclosed |