Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659740 | 0.97 | MEN1 (0.46) | MEN1KMT2ANPSR1MAPTUSP2 | |
| SCHEMBL8659386 | 0.94 | NPSR1 (0.43) | MEN1KMT2ANPSR1MAPTALDH1A1 | |
| SCHEMBL8658960 | 0.90 | KMT2A (0.49) | MEN1KMT2ANPSR1MAPTUSP2 | |
| SCHEMBL8659850 | 0.89 | MEN1 (0.51) | MEN1KMT2ANPSR1MAPTUSP2 | |
| SCHEMBL8658863 | 0.89 | MEN1 (0.43) | MEN1KMT2ANPSR1MAPTUSP2 | |
| SCHEMBL9135134 | 0.88 | MEN1 (0.46) | MEN1KMT2ANPSR1MAPTUSP2 | |
| SCHEMBL8659373 | 0.88 | NPSR1 (0.43) | MEN1KMT2ANPSR1MAPTALDH1A1 | |
| SCHEMBL8659368 | 0.85 | GCGR (0.43) | KMT2ANPSR1MAPTALDH1A1GCGR | |
| SCHEMBL8659541 | 0.85 | ATM (0.44) | MEN1KMT2ANPSR1MAPTALDH1A1 | |
| SCHEMBL8659795 | 0.84 | KMT2A (0.49) | MEN1KMT2ANPSR1MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| US-4602109-A | Novel pesticidal phenoxyphenyl and phenoxypyridyl benzoyl ureas and process for preparation | UNION CARBIDE CORPORATION (US) | 1986-07-22 | — | — | US | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| US-4540578-A | Pesticidal phenoxypyridyl benzoyl ureas | UNION CARBIDE CORPORATION (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0113247-A1 | Pesticidal phenoxyphenyl and phenoxypyridyl benzoyl ureas and process for their preparation | UNION CARBIDE CORPORATION (US) | 1984-07-11 | — | — | EP | disclosed |