SCHEMBL8657357

SCHEMBL8657357

C=CCC(C)(CCCCCCCCCCC)OP(O)(O)=S

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 5/20 0.40
LPAR2 Q9HBW0 4/20 0.40
SMPD1 P17405 5/20 0.39
LPAR1 Q92633 2/20 0.37
GGPS1 O95749 6/20 0.36
FDPS P14324 9/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25873491 0.85 LPAR3 (0.48) LPAR3LPAR2SMPD1LPAR1GGPS1
SCHEMBL5184205 0.76 TSHR (0.35) SMPD1GGPS1FDPS
SCHEMBL17060726 0.70 TSHR (0.39) SMPD1FDPS
SCHEMBL9585050 0.68 TSHR (0.46) LPAR3LPAR1GGPS1FDPS
SCHEMBL4733861 0.68 TSHR (0.46) LPAR3LPAR1GGPS1FDPS
SCHEMBL27879310 0.68 TSHR (0.46) LPAR3LPAR1GGPS1FDPS
SCHEMBL1277109 0.68 TSHR (0.46) LPAR3SMPD1LPAR1GGPS1FDPS
SCHEMBL9445608 0.68 TSHR (0.46) LPAR3SMPD1LPAR1GGPS1FDPS
SCHEMBL21625685 0.68 TSHR (0.41) SMPD1GGPS1FDPS
SCHEMBL7609298 0.67 LPAR3 (0.44) LPAR3LPAR2SMPD1LPAR1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531585-B1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LTD (GB) 1998-11-04 EP disclosed
US-5464549-A Oil soluble dispersants suitable for use in fuels and lubricants ETHYL CORPORATION (US) 1995-11-07 US disclosed
US-5358652-A Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1994-10-25 US disclosed
US-5241003-A Post-treated polyisobutenyl succinimide; crankcase, transmission oils ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-08-31 US disclosed
EP-0531585-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-03-17 EP disclosed
US-5137980-A Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-08-11 US disclosed