Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28992962 | 0.90 | KDM4E (0.81) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL6127192 | 0.84 | KDM4E (0.89) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL4578943 | 0.84 | KDM4E (0.77) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL4578939 | 0.84 | KDM4E (0.77) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL1905615 | 0.82 | KDM4E (0.74) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL10358749 | 0.82 | KDM4E (0.74) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL3077089 | 0.82 | KDM4E (0.74) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL16181983 | 0.81 | KDM4E (0.68) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL18906066 | 0.81 | KDM4E (0.83) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL31169755 | 0.81 | KDM4E (0.72) | KDM4ENPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834493-A | TREATMENT OF NERVOUS SYSTEM DISORDERS | GIL QUINTERO MYRNA (IT) | 1998-11-10 | — | — | US | disclosed |
| EP-0694033-A1 | INDOLE DERIVATIVES AS 5-HT1A AND/OR 5-HT2 LIGANDS | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1996-01-31 | — | — | EP | disclosed |
| WO-1994024125-A1 | INDOLE DERIVATIVES AS 5-HT1A AND/OR 5-HT2 LIGANDS | BOEHRINGER INGELHEIM ITALIA S.P.A. (IT) | 1994-10-27 | — | — | WO | disclosed |