Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 4/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.38 |
| ▸ | PRKCG | P05129 | 3/20 | 0.38 |
| ▸ | PRKCB | P05771 | 3/20 | 0.38 |
| ▸ | PRKCH | P24723 | 3/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636458 | 0.97 | PTPRC (0.42) | PTPRCCCNT1CDK9CCNE2CDK4 | |
| SCHEMBL8657563 | 0.96 | PTPRC (0.41) | PTPRCCCNT1CDK9CCNE2CDK4 | |
| Hydrochloric Acid SCHEMBL8653000 | 0.84 | PTPRC (0.40) | PTPRCCCNT1CDK9CCNE2CDK4 | |
| Hydrochloric Acid SCHEMBL8654746 | 0.83 | PRKD3 (0.44) | PTPRCPRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL8656527 | 0.83 | PTPRC (0.39) | PTPRCCCNT1CDK9CCNE2CDK4 | |
| Hydrochloric Acid SCHEMBL8655119 | 0.83 | PRKD3 (0.41) | PTPRCCCNE2CDK4CCND1CCNE1 | |
| SCHEMBL8657717 | 0.81 | PRKCE (0.44) | PTPRCPRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL8659809 | 0.81 | PRKD3 (0.40) | PTPRCCCNT1CDK9PRKCAPRKD3 | |
| SCHEMBL8655464 | 0.81 | PRKCE (0.59) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| Acetic Acid SCHEMBL8656361 | 0.80 | PRKCE (0.50) | PRKCAPRKD3PRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721245-A | ANTIINFLAMMATORY AGENTS, RESPIRATORY SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1998-02-24 | — | — | US | disclosed |