SCHEMBL8657668

SCHEMBL8657668

CCCCCCCCCCCCCOP(O)(=S)OCCCCCCCCCCCCC

nearest known ligand 0.75

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 19/20 0.75
LPAR2 Q9HBW0 15/20 0.75
LPAR1 Q92633 13/20 0.61
LPAR6 P43657 5/20 0.50
LPAR4 Q99677 5/20 0.50
LPAR5 Q9H1C0 5/20 0.50
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40048 1.00 LPAR3 (0.75) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL8467562 1.00 LPAR3 (0.75) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL8467950 1.00 LPAR3 (0.75) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL7256485 1.00 LPAR3 (0.75) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL482324 1.00 LPAR3 (0.75) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL8658599 1.00 LPAR3 (0.75) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL6692742 1.00 LPAR3 (0.75) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL2151049 1.00 LPAR3 (0.75) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL1971188 1.00 LPAR3 (0.75) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL14053589 0.98 LPAR3 (0.72) LPAR3LPAR2LPAR1LPAR6LPAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531585-B1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LTD (GB) 1998-11-04 EP disclosed
US-5464549-A Oil soluble dispersants suitable for use in fuels and lubricants ETHYL CORPORATION (US) 1995-11-07 US disclosed
US-5358652-A Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1994-10-25 US disclosed
US-5241003-A Post-treated polyisobutenyl succinimide; crankcase, transmission oils ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-08-31 US disclosed
EP-0531585-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-03-17 EP disclosed
US-5137980-A Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-08-11 US disclosed