SCHEMBL8658643

SCHEMBL8658643

C=CCOP(=O)(O)OCCCCCCCCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 12/20 0.56
LPAR2 Q9HBW0 10/20 0.56
LPAR1 Q92633 5/20 0.56
TSHR P16473 1/20 0.45
P2RY10 O00398 1/20 0.44
LPAR5 Q9H1C0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1048527 1.00 LPAR3 (0.56) LPAR3LPAR2LPAR1TSHRP2RY10
SCHEMBL28985849 1.00 LPAR3 (0.56) LPAR3LPAR2LPAR1TSHRP2RY10
SCHEMBL7214426 1.00 LPAR3 (0.56) LPAR3LPAR2LPAR1TSHRP2RY10
SCHEMBL7251103 1.00 LPAR3 (0.56) LPAR3LPAR2LPAR1TSHRP2RY10
SCHEMBL474838 0.98 LPAR3 (0.53) LPAR3LPAR2LPAR1TSHRP2RY10
SCHEMBL28121302 0.93 LPAR3 (0.49) LPAR3LPAR2LPAR1TSHRP2RY10
SCHEMBL28985780 0.93 CYP3A4 (0.47) LPAR3LPAR2LPAR1TSHRP2RY10
SCHEMBL9301546 0.92 LPAR3 (0.60) LPAR3LPAR2LPAR1P2RY10
SCHEMBL9301534 0.92 LPAR3 (0.60) LPAR3LPAR2LPAR1P2RY10
Ether SCHEMBL29917 0.92 LPAR3 (0.47) LPAR3LPAR2LPAR1TSHRP2RY10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531585-B1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LTD (GB) 1998-11-04 EP disclosed
US-5464549-A Oil soluble dispersants suitable for use in fuels and lubricants ETHYL CORPORATION (US) 1995-11-07 US disclosed
US-5358652-A Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1994-10-25 US disclosed
US-5241003-A Post-treated polyisobutenyl succinimide; crankcase, transmission oils ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-08-31 US disclosed
EP-0531585-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-03-17 EP disclosed
US-5137980-A Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-08-11 US disclosed